Published by: NISCAIR (CSIR)
Indian Journal of Chemistry (Section B) is published by the National Institute of Science Communication and Information Resources (NISCAIR)-CSIR, New Delhi. This journal publishes articles in Organic and Medicinal Chemistry. It includes full length papers, notes and communications and short reviews. The monthly issues covers articles in organic reaction mechanism, theoretical organic chemistry, structure-activity relationships, medicinal chemistry, synthesis of chiral compounds, bio-organic chemistry, enzymes in organic synthesis, reagents in organic synthesis, heterocyclic compounds, phytochemistry (natural products), amino acids, peptides and proteins, spectroscopy in characterization of organic compounds, chemoenzymatic and enantioselective synthesis of organic compounds, synthesis of fullerenes, metal-catalyzed asymmetric reactions, bioactive plant products and combinatorial chemistry.
Dr. P Paravatharajan
ISSN No. : 0376-4699
Subscribe to Recent articles by email
Synthesis of a new class of bis heterocycles
Title: Synthesis of a new class of bis heterocycles
Authors: Padmavathi, Venkatapuram; Sreelatha, Tumma; Reddy, Putta Ramachandra; Divya, Kuppireddygari
Abstract: A variety of bis
heterocycles-oxazolyl / thiazolyl / imidazolyl pyrroles and pyrazoles have been
prepared adopting 1,3-dipolar cycloaddition of tosylmethyl isocyanide and
diazomethane to oxazolyl / thiazolyl / imidazolyl acrylamides.
Catalyst-free access to pseudo multi-component synthesis of benzopyranopyrimidines
Title: Catalyst-free access to pseudo multi-component synthesis of benzopyranopyrimidines
Authors: Shaikh, T S; Patil, J D; Gaikwad, D S; Hegade, P G; Patil, P B; Undale, K A; Mane, M M; Pore, D M
Abstract: A catalyst-free multi-component
reaction of salicylaldehyde, malononitrile and secondary amine leads to the formation
of benzopyranopyrimidines with intense fluorescence emission behavior is described.
The method is simple, eco-friendly, economic, operable under mild conditions, having
short reaction time, high yields and easy work-up procedure which suggests broad
applicability of the protocol.
Lupane-triterpenoids from stem bark of Dillenia indica
Title: Lupane-triterpenoids from stem bark of Dillenia indica
Authors: Ghosh, Partha Sarathi; Sarma, Indrajit Sil; Sato, Noriko; Harigaya, Yoshihiro; Dinda, Biswanath
Abstract: A new
lupane-triterpene acid ester, dillenic acid 1 along with four known compounds, betulinic acid 2, 3-epi-betulinic acid 3,
3-epi-dihydrobetulinic acid 4 and
3α-hydroxy-lup-20(29)-en-23,28-dioic acid 5
have been isolated from the stem bark of
Dillenia indica Linn (Dilleniaceae). Based on spectroscopic and chemical
data, the structure of the new compound 1
was determined as 3α-(2-hydroxyhexanoyloxy)-lup-20(29)-en-28-oic acid. Known
compounds 3-5 has been reported for
the first time from this plant.
Synthesis of novel isoxazolo[2'',3'':1',2']pyrimido[4',5':4,5]pyrimido- [6,1-b]quinazoline-8-ones and their in vitro anticancer and antimicrobial activities
Title: Synthesis of novel isoxazolo[2'',3'':1',2']pyrimido[4',5':4,5]pyrimido- [6,1-b]quinazoline-8-ones and their in vitro anticancer and antimicrobial activities
Authors: Rajanarendar, E; Kishore, B; Ramakrishna, S; Nagaraju, D; Venkateshwarlu, P
Abstract: Synthesis of novel
has been achieved by reaction of 5-amino-2-methyl-7-phenyl-7H-isoxazolo[2,3-a] pyrimidin-6-yl
cyanides 4, with dimethyl formamide
dimethylacetal followed by treatment with anthranilic acids in situ in one-pot. The key
5-amino-2-methyl-7-phenyl-7H-isoxazolo[2,3-a]pyrimidin-6-yl cyanide 4 is obtained by reaction of
3-amino-5-methyl isoxazole with aromatic aldehydes and malononitrile by a
three-component one-pot process. The newly synthesized compounds 6a-j have been evaluated for their in vitro anticancer and antimicrobial
activity. Compounds 6e and 6f exhibit potent anticancer and
antimicrobial activity comparable to that of standard drugs.
Back to Journals