Indian Journal of Chemistry: Sec B- Organic Chemistry including Medicinal Chemistry

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Published by: NISCAIR (CSIR)

Subjects: Chemistry

Indian Journal of Chemistry (Section B) is published by the National Institute of Science Communication and Information Resources (NISCAIR)-CSIR, New Delhi. This journal publishes articles in Organic and Medicinal Chemistry. It includes full length papers, notes and communications and short reviews. The monthly issues covers articles in organic reaction mechanism, theoretical organic chemistry, structure-activity relationships, medicinal chemistry, synthesis of chiral compounds, bio-organic chemistry, enzymes in organic synthesis, reagents in organic synthesis, heterocyclic compounds, phytochemistry (natural products), amino acids, peptides and proteins, spectroscopy in characterization of organic compounds, chemoenzymatic and enantioselective synthesis of organic compounds, synthesis of fullerenes, metal-catalyzed asymmetric reactions, bioactive plant products and combinatorial chemistry.

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Editor,
Dr. P Paravatharajan
email: prema@niscair.res.in


ISSN No. :    0376-4699
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Ecofriendly synthesis of some benzothiazoles containing acridine moiety and their antimicrobial acitivity
Title: Ecofriendly synthesis of some benzothiazoles containing acridine moiety and their antimicrobial acitivity

Authors: Kawle, P R; Deohate, P P; Berad, B N

Abstract: Syntheses of benzothiazoles containing acridine moiety have been attempted by employing microwave irradiation method. (Acridin-9-yl-amino)-acetic acid N-(benzothiazol-2-yl)-hydrazides have been achieved by intramolecular oxidative cyclisation of (acridin-9-yl-amino)-acetic acid N-(N’-aryl-thioamido)-hydrazides using bromine in acetic acid. The required hydrazides have been synthesized by the interaction of (acridin-9-yl-amino)-acetic acid hydrazides with N-aryl isothiocyanates under microwave condition at 800 W. The structural elucidations of synthesised compounds have been performed by IR, 1H NMR and mass spectroscopic data and elemental analysis. The developed route is found to be satisfactory with improved yields, easy work-up and no environmental pollution. All the compounds have been found to possess potent antimicrobial response.

Page(s): 833-836

Highly efficient tandem syntheses of unsymmetrically substituted isomeric S,N-disubstituted-2-mercaptobenzimidazoles
Title: Highly efficient tandem syntheses of unsymmetrically substituted isomeric S,N-disubstituted-2-mercaptobenzimidazoles

Authors: Rao, S Srinivas; Reddy, Ch Venkata Ramana; Dubey, P K

Abstract: Highly efficient tandem syntheses of unsymmetrically substituted isomeric S,N-disubstituted-2-mercaptobenzimidazoles have been developed. The structures of 6a-d and isomeric compounds 9a-d have been synthesized from 2-mercaptobenzimi-dazole using tandem synthesis. The structures of 6a-d and isomeric compounds 9a-d have been established by spectral and analytical data, and by unambiguous syntheses.

Page(s): 829-832

Synthesis of β-aminoketone by reaction of amine and activated chalcone in microwave irradiation
Title: Synthesis of β-aminoketone by reaction of amine and activated chalcone in microwave irradiation

Authors: Yuvaraj, Panneerselvam; Kathirvelan, D; Reddy, Boreddy S R

Abstract: A simple and efficient protocol has been developed for the aza-Michael addition of amines to a variety of activated olefins or chalcones under microwave irradiation. Under these conditions, there is a significant decrease in the reaction time while considerable increase in the yield and purity of the products can be obtained.

Page(s): 825-828

Eco-friendly and ingenious multicomponent synthesis of N-arylquinolines using DABCO/TEAB in water
Title: Eco-friendly and ingenious multicomponent synthesis of N-arylquinolines using DABCO/TEAB in water

Authors: Singh, Satish Kumar; Jena, Sambedan

Abstract: An easy, improved, and environmentally benign synthesis of N-arylquinolines is reported via one-pot multicomponent reaction of aromatic aldehydes, active methylene compounds and 3-arylamino-5,5-dimethylcyclohex-2-enone utilizing catalytic amount of combined diazabicyclo-2,2,2-octane (DABCO) and tetraethyl-ammonium bromide (TEAB) in water under reflux in excellent yields.

Page(s): 821-824

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